David S Bredt Selected Research

AMPA Receptors (AMPA Receptor)

1/2019	Modulation of TARP γ8-Containing AMPA Receptors as a Novel Therapeutic Approach for Chronic Pain.
12/2017	Getting a Handle on Neuropharmacology by Targeting Receptor-Associated Proteins.
12/2016	Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism.
11/2007	AMPA receptors and stargazin-like transmembrane AMPA receptor-regulatory proteins mediate hippocampal kainate neurotoxicity.
7/2002	Phosphorylation of the postsynaptic density-95 (PSD-95)/discs large/zona occludens-1 binding site of stargazin regulates binding to PSD-95 and synaptic targeting of AMPA receptors.

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David S Bredt Research Topics

Disease

4	Pain (Aches) 11/2020 - 07/2003
4	Epilepsy (Aura) 12/2017 - 09/2006
4	Herpes Zoster 05/2008 - 07/2002
3	Seizures (Absence Seizure) 11/2007 - 12/2002
2	Neuralgia (Stump Neuralgia) 11/2020 - 11/2003
2	Chronic Pain 01/2019 - 11/2003
2	Hyperalgesia 01/2019 - 11/2003
2	Neurodegenerative Diseases (Neurodegenerative Disease) 09/2007 - 06/2006
2	Peripheral Nerve Injuries 11/2003 - 07/2003
1	Deafness (Deaf Mutism) 01/2020
1	Dizziness (Lightheadedness) 12/2016
1	Bipolar Disorder (Manic Depressive Psychosis) 05/2010
1	Schizophrenia (Dementia Praecox) 05/2010
1	Shellfish Poisoning 11/2007
1	Autosomal Dominant Lateral Temporal Lobe Epilepsy 09/2006
1	Ischemia 09/2004
1	Brain Diseases (Brain Disorder) 09/2004
1	Traumatic Brain Injuries (Traumatic Brain Injury) 09/2004
1	Ganglion Cysts (Ganglion) 01/2004
1	Acute Pain 07/2003

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 01/2020 - 07/2002
5	AMPA Receptors (AMPA Receptor)IBA 01/2019 - 07/2002
3	Cholinergic Agents (Cholinergics)IBA 11/2020 - 01/2004
3	TARPIBA 01/2019 - 05/2010
2	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 11/2020 - 01/2020
2	LigandsIBA 01/2020 - 09/2006
2	Glutamic Acid (Glutamate)FDA Link 01/2019 - 11/2007
2	Guanylate KinasesIBA 05/2008 - 08/2002
2	Ion Channels (Ion Channel)IBA 09/2007 - 09/2006
2	Freund's AdjuvantIBA 11/2003 - 07/2003
1	Nicotine FDA Link 11/2020
1	Opioid Analgesics (Opioids)IBA 11/2020
1	Pharmaceutical PreparationsIBA 01/2020
1	LY3130481IBA 01/2019
1	AcidsIBA 01/2019
1	perampanelIBA 12/2016
1	domoic acidIBA 11/2007
1	Kainic Acid (Kainate)IBA 11/2007
1	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 11/2007
1	Glutamate Receptors (Glutamate Receptor)IBA 09/2007
1	Platelet Activating FactorIBA 09/2004
1	OligodeoxyribonucleotidesIBA 11/2003
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 07/2003
1	Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA 12/2002

Therapy/Procedure

3	Therapeutics 01/2019 - 11/2003
1	Ligation 01/2019